17
Feb
He would only do IUI with injectables if I wanted to but recommends I move straight to donor eggs based on the AMH test. After each IVF attempt the doctor will again prescribe an analysis to determine AMH in order to monitor the performance of the ovaries and correct the next attempt if the previous one failed.
This is not mathematics purely as till now many factors influencing IVF success rates are under research.
Chances of ivf success with low amh. Resulting laboratory figures of the AMH test can be divided as follows. Less than 1 ngml low ovarian reserve and worse results for ovarian stimulation in fertility treatments 1-3 ngml levels considered normal and above 3 ngml good reserve but special attention required in case of the ovarian stimulation. Circulating anti-müllerian hormone AMH and antral follicle count AFC are the best predictors of IVF outcomes.
However in extreme low AMH range especially for young patients AMH prediction power loose its specificity to give real idea of pregnancy chance with IVF treatments and good prognosis of an extremely reduced ovarian reserve and expected poor response. IVF success rates range anywhere between 20 - 40 depending on various factors. This is not mathematics purely as till now many factors influencing IVF success rates are under research.
The most important factors are -. By the way AMH and AFC from what Ive read dont have much predictive value for your success with natural conception but theyre indicative of how youll respond to IVF ie. Someone with a low AMH will get low numbers of eggs in IVF which obviously means lower odds but in a natural cycle they still release just 1 egg same as someone with a high AMH.
Your AFC and low egg counts are tied to your low AMH but all is not lost. Just because youre not producing a ton of follicleseggs does NOT mean that the ones you do produce will not be excellent quality. Also its still a bit early in your stim cycle and a few more could pop up before you retrieve.
In this case the doctor recommends using in vitro fertilization with donor oocytes. The chances of getting pregnant and carrying a baby are much higher. After each IVF attempt the doctor will again prescribe an analysis to determine AMH in order to monitor the performance of the ovaries and correct the next attempt if the previous one failed.
I found out I had low AMH 016 when I was 37. My FSH ranges from 13-29 AFC 1-3. I started IVF right away with a poor response only 2 eggs retrieved one fertilized.
Decided to try mini IVF and bank embryos 3 cycles only one follicle each cycle one egg retrieved each time all fertilized made it to blasts. There was no difference in the outcome of IVF between patients with low and extremely low AMH levels. Women with normal AMH level resulted in a higher pregnancy rate as compared to women with low AMH level in the same age group.
Age is important in determining prognosis of IVF in patients with low levels of AMH. Can you still get pregnant with low AMH. Yes you can still get pregnant with low AMH.
It is just statistically more difficult and this is why fertility doctors often suggest IVF or even an egg donor to increase your odds. After being told the chances of IVF were low and my eggs being described as rotten apples I went on to have a cycle of IVF which resulted in no eggs being fertilised due to poor quality. I then went on to have ICSI which resulted in 3 eggs being fertilised 2 made it to blastocyst one is now a 21 month year old girl and the other is in the freezer.
The new RE says there is no point doing IVF with that AMH result. He said my chances of success are less than 2. He said you usually get half the number of eggs of your AMH so I would be lucky to get 1.
He would only do IUI with injectables if I wanted to but recommends I move straight to donor eggs based on the AMH test. IVF and low AMH I asked Professor Geeta Nargund the founder. If tests show that a woman has a low Anti-Mullerian Hormone AMH level then this indicates that she also may have a low ovarian reserve will need an ultrasound scan of the ovaries and may need medical.
IVF with Low AMH levels The chances of a successful pregnancy will depend on a womans ovarian reserve and for them IVF is a potential option which can make optimal use of the limited eggs left in their ovaries. Provided the matured egg retrieved in a specific IVF. Hi LB It is possible to improve the quality of your eggs naturally in order to ensure a successful IVF cycle.
How well this will work really depends on your general state of health your age and how low your AMH level really is. I think its worth trying a natural approach before resorting to egg donor. My AMH a year ago was 028 so its probably close to undetectable levels now planning on asking for a re-test this week.
My RE is still suggesting IVF with my own eggs even though everything Ive read online says that IVF success rates for women with AMH levels in this range are extremely low and most REs would advise using donor eggs. Between January 2006 and October 2009 128 consecutive infertility patients with AMH 04 ngml were retrospectively evaluated for pregnancy chances and live birth rates after IVF. Patients presented at a mean SD age of 408 41 years with mean SD baseline FSH of 157 111 mIUml and mean SD AMH of 02 01 ngml.
This means that if you have a lower AMH level it doesnt necessarily mean that you have lower IVF chances because you may have other fertility factors that could be acting in your favour and create a more enhanced fertility prognosis than we would expect based on the AMH test results alone. A score below 5 will generally mean a low chance of successful treatment. So your AMH test lets you and your doctor make an informed choice on whether or not to go ahead.
A reasonably high rather than a reasonably low AMH score is generally best. More follicles usually mean more collected eggs after IVF stimulation. When the IVF outcomes were compared between the two groups with discrepancies between age and the AMH level the young low-AMH group and older high-AMH group it was found that the number of oocytes retrieved 915 509 vs 1291 573 p 001 the number of 2PN zygotes 532 359 vs 779 439 p 001 and the frequency of GQE 242 253 vs 360 332 p 001 were significantly lower in the young low-AMH group than in the older high-AMH.
In fact IVF gives such women better chances to conceive because it makes the optimal use of the few eggs which are left in their ovarian reserve. In cases where even IVF treatment brings no hope for such patients donor eggs may be considered as the next option. If you have very low AMH levels you can still get pregnant with the right treatment.
Treating low AMH levels is not even a branch of science. Medicine currently pays it no heed. IVF drugs try to grow as many eggs as they can.
IVF success hinges on the ability to develop good eggs. The more eggs they can grow the higher the chance of a successful pregnancy. It has been this way since 1984 and the IVF treatment agenda has not changed.
The aggressive IVF stimulation and augmentation protocols that we use for patients with low ovarian reserve might account for the high success rates. Conclusions High AMH levels correlate with low cancellation rates retrieval of more eggs higher live birth rates and a high chance for cryopreservation. In summary FSH andor AMH are predictive of IVF outcomes to a degree because both represent FOR and FOR in turn is reflective of egg and embryo numbers obtained in an IVF cycle which is the second most important predictor of IVF success.
The most important predictor of IVF success is the female age Quite a number of additional factors including how ovaries are stimulated also influence IVF outcomes and in isolation FSHAMH. In recent years AMH has emerged as a predictor of ovarian response to drug stimulation in IVFA study from Scotland has proposed that women with very low AMH concentration are at risk of either cycle cancellation or poor response to ovarian stimulation. For example AMH like ovarian reserve decreases with age.
Some studies in IVF patients have shown lower AMH levels in women who responded poorly to fertility drugs. Recently doctors studied 48 women who were attempting to achieve pregnancy with IVF for the first time. The women varied in age from 25 to 43.